Previously Funded:
Los Alamos National Lab (LANL)/LDRD:
Director's Postdoc Fellowship: Optical imaging of neural function;
FUNDING PERIOD: 09/1997-08/1999;
TOTAL DIRECT COSTS: $160,000;
ROLE: Principal Investigator;
EFFORT: 100%
Los Alamos National Lab (LANL)/LDRD:
Director's Postdoc Fellowship: Virtual pinhole confocal microscope;
FUNDING PERIOD: 03/1999-11/2001;
TOTAL DIRECT COSTS: $100,000;
ROLE: Principal Investigator;
EFFORT: 100%
Los Alamos National Lab (LANL)/LDRD:
Optical studies of neural function in vision, characterization of intrinsic responses;
FUNDING PERIOD: 07/2000-09/2003;
TOTAL DIRECT COSTS: $200,000/year for 3 years;
ROLE: Investigator (PI: J.S. George);
EFFORT:20%
Department of Energy (DOE):
Retinal prosthesis;
FUNDING PERIOD:10/200-09/2004;
TOTAL DIRECT COSTS: $400,000/ year, 5 years;
ROLE: Investigator (PI: J.S. George);
EFFORT: 20%
NFFBI/MIND:
Mechanisms of optical response;
FUNDING PERIOD: 02/2001-06/2002;
TOTAL DIRECT COSTS: $60,000;
ROLE: Principal Investigator;
EFFORT: 25%
Sleep Research Society:
Chris J. Gillin Jr. Faculty Development Award;
FUNDING PERIOD: 07/2001-06/2004;
TOTAL DIRECT COSTS: $135,000/year, for 3 years;
ROLE: Principal Investigator;
EFFORT: 25%
Currently Funded:
NIH/NIMH [#MH60623]:
Advanced image probe for neurophysiology;
FUNDING PERIOD: 07/2001-06/2010;
TOTAL DIRECT COSTS: $225,000/year for 4 years (renewed);
ROLE: Principal Investigator;
EFFORT: 25% ;
AIMS: To develop and apply advanced imaging devices and techniques to the detection of scattered light signals from neural tissue.;
NOTE: This grant was accepted for a competetive renewal in 2005.
Beckman Foundation:
Beckman Young Investigators Award: Spatial-temporal dynamics of cortical high-frequency (200-600 Hz) oscillations and their role in rat somatosensory processing;
FUNDING PERIOD: 03/2004-02/2007;
TOTAL DIRECT COSTS: $80,000/year, for 3 years;
ROLE: Principal Investigator;
EFFORT: 0%
M.J. Murdock Charitable Trust:
Near infrared optical brain imaging of sleep;
FUNDING PERIOD: 10/2005 - 09/2006;
TOTAL DIRECT COSTS: $50,000;
ROLE: Principal Investigator;
EFFORT: 0%;
AIMS: The major goals of this project are to develop optical techniques to record EEG in humans.
NIH [MH071830-01]:
Implantable 16-256 channel data system for sleep in mice;
FUNDING PERIOD: 01/2006 - 12/2010;
TOTAL DIRECT COSTS: $225,000/year, for 5 years;
ROLE: Principal Investigator;
EFFORT: 25%;
AIMS: The major goals of this project are to develop an implantable amplifier and digitizer for remote recording of physiology from mice.
NIH/NIMH:
Interleukin-1: promoter of slow wave sleep;
FUNDING PERIOD: 03/2005 - 02/2010;
TOTAL DIRECT COSTS: $250,000/year, for 5 years;
ROLE: Co-PI;
EFFORT: 5%;
AIMS: To help establish a unique view of biochemical sleep mechanisms and to thereby significantly impact sleep medicine and sleep research.
NIH/NIMH [#NS31453]:
Sleep regulation and tumor necrosis factor;
FUNDING PERIOD: 12/2006-11/2011;
TOTAL DIRECT COSTS: $250,000/year, for 5 years;
ROLE: Investigator (PI: J.M. Krueger);
EFFORT: 10%;
AIMS: The major goals of this project are to determine which TNF receptor is involved in sleep regulation, whether TNF or TNF-alpha mRNA varies in brain with the time of day or after sleep deprivation, and to localize where in the brain sleep-linked changes in TNF occur.
NIH/NIMH: R21DA020125
Cocaine, Electroconvulsive Seizure and Neural Plasticity;
FUNDING PERIOD: 04/2006-03/2008;
TOTAL DIRECT COSTS: $275,000
ROLE: Investigator (PI: B.A. Sorg);
EFFORT: 15%;
AIMS: The major goals of this project are to determine the effects of seizure duration and number days of ECS treatment on reinstatement of cocaine-primed CPP and to optimize the timing of ECS treatment for its ability to suppress reinstatement of cocaine-primed CPP.
Aculight Corporation:
Facial and Vagus Nerve Stimulation in Rats;
FUNDING PERIOD: 09/2006 - 08/2007;
TOTAL DIRECT COSTS: $14,639;
ROLE: Principal Investigator;
EFFORT: 0%;
AIMS: To evaluate the transient optical neural stimulation (TONS) for stimulation of the trigeminal and vagus nerves.
W.M. Keck Foundation:
Testing a New Theory of Brain Organization in Sleep;
FUNDING PERIOD: 2007-2009;
TOTAL DIRECT COSTS: $1,494,057;
ROLE: Investigator (PI: G. Belenky);
EFFORT: 0%;
AIMS: The major goals of this project are to 1)define functional sleep states in rat and human cortical columns and show they have sleep homeostatic qualities, 2)demonstrate that behavioral performance is dependent on cortical column state in rat and humans, and 3)to assess in rats and humans the metabolic changes in cortical columns that give rise to the functional sleep state.
Grants Submitted and Pending
NIH [NS053451-01]:
CMOS sensor development for real-time imaging of neural activity;
PROPOSED FUNDING PERIOD: 01/2006 - 12/2007;
TOTAL DIRECT COSTS: $125,000;
ROLE: Investigator (PI: J.F. Frenzel);
EFFORT: 5%;
AIMS: The major goals of this project are to develop an implantable camera device for small animals.
NIH [NS048941-01]:
Markers of sleep/wake-like states in cortical columns;
PROPOSED FUNDING PERIOD: 07/2004 - 06/2009;
TOTAL DIRECT COSTS: $250,000/year, for 5 years;
ROLE: Principal Investigator;
EFFORT: 35%;
AIMS: The major goals of this project are to characterize sleep-like evoked responses within individual cortical columns.
NIH/NIMH [MH076626-01]:
Optics in biomedicine student trainee workshop;Back / Index / Next
PROPOSED FUNDING PERIOD: 04/2006 - 04/2006;
TOTAL DIRECT COSTS: $49,000;
ROLE: Principal Investigator;
EFFORT: 0%;
AIMS: The major goals of this project are to train students to collaborate within an interdisciplinary environment.